红色石匠蜜蜂的遗传映射表明,ANTSR是蜜蜂和中古代的性别决定地点
Tilman Rönneburg1, Demetris Taliadoros1, Anna Olsson1
1Department of Medical Microbiology and Biochemistry, SciLifeLab, Uppsala University, Uppsala, Sweden.
PLoS biology
|November 3, 2025
概括
研究人员在红色石匠蜜蜂Osmia bicornis中确定了性别决定的位置. 这种与ANTSR基因相关的补充性决定 (CSD) 位点,在蜜蜂和中似乎是祖先的.
科学领域:
- 遗传学 是一个遗传学.
- 进化生物学 进化生物学
- 昆虫学 昆虫学是一门学科.
背景情况:
- 在蝶中常见的哈普洛迪普洛伊德遗传,依赖于补充性决定 (CSD) 位点来确定性别.
- 具体的中央证券交易所位置因物种而异,其身份在大多数情况下仍然未知.
研究的目的:
- 为了绘制红色石匠蜜蜂 (Osmia bicornis) 中的CSD位点.
- 为了研究进化历史和潜在的广泛的作用,这个地方在Hymenoptera.
主要方法:
- 在奥斯米亚双角虫的2kbp基因组区域内微绘一个单一的CSD位点.
- 在CSD位置分析哈普洛型多样性和异构性模式.
- 在其他五个蜜蜂和属中对CSD locus ortholog进行比较分析.
主要成果:
- 一个单一的CSD位点被映射到Osmia bicornis中的2kbp区域,重叠长非编码RNA ANTSR.
- 该位点显示出高哈普洛型多样性和异构性,与频率依赖的选择相一致.
- 在多个蜜蜂和物种的正确位置中观察到较高的遗传多样性.
结论:
- ANTSR基因被确定为奥斯米亚双角虫的性别决定基因.
- 这些发现表明,ANTSR是蜜蜂和的祖先性别决定位置,其作用在1.5亿年前已经演变.
- 这种位置很可能在Hymenoptera中广泛控制性别决定.
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