Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

2.6K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
2.6K
Other Unique Bacteria01:18

Other Unique Bacteria

405
Magnetic bacteria exhibit a directed movement called magnetotaxis, driven by structures called magnetosomes. These magnetosomes consist of chains of magnetic particles made of either magnetite (Fe₃O₄) or greigite (Fe₃S₄) and are organized in a linear conformation by a protein scaffold within invaginations of the cell membrane. The bacteria align along the north–south magnetic field lines, much like a compass needle. They are typically microaerophilic or anaerobic...
405
Bacterial Signaling01:30

Bacterial Signaling

40.0K
Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
40.0K
Antibiotic Selection00:57

Antibiotic Selection

59.3K
Overview
59.3K
Key Techniques in Microbiology01:19

Key Techniques in Microbiology

1.4K
Aseptic techniques prevent contamination, ensure experimental accuracy, and protect researchers and microbial cultures. These techniques are essential in clinical, industrial, and research settings where sterility is required.Maintaining Sterility in Laboratory PracticesScientists maintain sterility by sterilizing tools with heat or chemicals, disinfecting work surfaces, and handling cultures in controlled environments. Working near an open flame or within a laminar flow hood reduces the risk...
1.4K
Stringent Response in E. coli01:23

Stringent Response in E. coli

285
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
285

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Multimodal control of Cas13d activity through domain insertion at an allosteric hotspot.

Nature communications·2026
Same author

Rorippa islandica is a genetically accessible dicot model system to study flooding tolerance.

Plant physiology·2026
Same author

Controlled Low-Oxygen Supply Enables Magnetosome Size Tuning by Uncoupling Magnetite Nucleation and Crystal Growth in Magnetospirillum gryphiswaldense.

Microbial biotechnology·2026
Same author

The assembly rules guiding hetero-oligomeric bacterioferritin organization and their evolutionary signature.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Ultrafast, remote-controlled protonation reaction enables structural changes in a phytochrome.

Science advances·2025
Same author

Spectroscopic Analyses of Photoconversion in Phytochromes.

Methods in molecular biology (Clifton, N.J.)·2025
Same journal

Frequency-dependent modulation of foveal contrast sensitivity by fine-scale exogenously triggered attention.

eLife·2026
Same journal

Estimating probabilities of malaria importation in southern Mozambique through modelling <i>P. falciparum</i> genomics and mobility patterns.

eLife·2026
Same journal

Conformational variability of HIV-1 Env trimer and viral vulnerability.

eLife·2026
Same journal

Disinformation elicits learning biases.

eLife·2026
Same journal

Correction: Generation of a transparent killifish line through multiplex CRISPR/Cas9mediated gene inactivation.

eLife·2026
Same journal

Differential regulation of hepatic macrophage fate by Chi3l1 in metabolic dysfunction-associated steatotic liver disease.

eLife·2026
查看所有相关文章

相关实验视频

Updated: Jan 12, 2026

Bacterial Detection & Identification Using Electrochemical Sensors
09:30

Bacterial Detection & Identification Using Electrochemical Sensors

Published on: April 23, 2013

28.9K

工程NIR视觉细菌的工程NIR视觉细菌的工程

Stefanie S M Meier1, Michael Hörzing1, Cornelia Böhm2,3

  • 1Department of Biochemistry, University of Bayreuth, Bayreuth, Germany.

eLife
|November 3, 2025
PubMed
概括
此摘要是机器生成的。

科学家们使用细菌光传感器设计了合成双组件系统 (TCS). 这些系统能够精确控制像大肠杆菌这样的细菌中近红外 (NIR) 光的基因表达.

关键词:
美国大肠杆菌 (E. coli).细菌的植物染色体.生物化学 生物化学化学生物学 化学生物学基因表达的基因表达方式接近红外光的近红外光.视觉遗传学 视觉遗传学这种传感器是histidine kinase.两个组成部分的系统系统.

更多相关视频

Atomic Force Microscopy Combined with Infrared Spectroscopy as a Tool to Probe Single Bacterium Chemistry
08:51

Atomic Force Microscopy Combined with Infrared Spectroscopy as a Tool to Probe Single Bacterium Chemistry

Published on: September 15, 2020

4.5K
'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens
11:31

'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens

Published on: July 8, 2011

14.0K

相关实验视频

Last Updated: Jan 12, 2026

Bacterial Detection & Identification Using Electrochemical Sensors
09:30

Bacterial Detection & Identification Using Electrochemical Sensors

Published on: April 23, 2013

28.9K
Atomic Force Microscopy Combined with Infrared Spectroscopy as a Tool to Probe Single Bacterium Chemistry
08:51

Atomic Force Microscopy Combined with Infrared Spectroscopy as a Tool to Probe Single Bacterium Chemistry

Published on: September 15, 2020

4.5K
'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens
11:31

'Bioluminescent' Reporter Phage for the Detection of Category A Bacterial Pathogens

Published on: July 8, 2011

14.0K

科学领域:

  • 合成生物学 合成生物学
  • 微生物学 微生物学
  • 遗传学 遗传学 是一个

背景情况:

  • 对基因表达的控制对发育和适应至关重要.
  • 细菌中的二元系统 (TCS) 将环境信号与基因表达联系起来.
  • 诱导基因表达在研究和生物技术中至关重要.

研究的目的:

  • 开发由近红外 (NIR) 光激活的新型合成TCS.
  • 为了实现细菌基因表达的精确和多重控制.
  • 为了研究合成系统中的浴-植物染色体的光感应特性.

主要方法:

  • 利用树生物的浴-植物色光传感器.
  • 为大肠杆菌和Agrobacterium tumefaciens构建合成TCS.
  • 使用NIR和可见光进行直角基因表达控制.

主要成果:

  • 通过NIR光实现了严格的基因表达激活.
  • 使用正交TCS证明了多重基因控制.
  • 观察到对红光的最小反应,尽管Bathy-phytochromes对可见光敏感.
  • 展示了TCS对光信号的高度非线性反应.

结论:

  • 合成TCS可以被设计为特定的基于光的基因控制.
  • 芭提-植物色素可以调整为NIR特异性或广泛光敏感性.
  • 光控制的基因表达在微生物学和合成生物学中提供了一个强大的工具.