在人口基因组数据中识别单一来源的罕见变异

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Updated: Jan 12, 2026

Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER
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Detection of Rare Genomic Variants from Pooled Sequencing Using SPLINTER

Published on: June 23, 2012

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Josh J Reynolds1, Vassiliki Koufopanou1, Austin Burt1

  • 1Department of Life Sciences, Imperial College London, Silwood Park, Ascot SL5 7PY, United Kingdom.

Molecular biology and evolution
|November 3, 2025
PubMed
概括

在大型基因组数据集中,反复发生的突变可能是常见的,可能会扭曲人口统计学分析. 新的方法准确地识别出单一来源的变异,改善了种群遗传研究.

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