在母乳养期间仅使用孕激素的避孕措施:更新的系统性审查
Angeline Ti1, Sylvia Ayieko2, Mercedes Bonet3
1Wellstar Douglas Family Medicine Residency Program, Douglasville, Georgia, USA angeline.ti@wellstar.org.
BMJ sexual & reproductive health
|November 3, 2025
概括
只有孕激素的避孕药 (POC) 对母乳养妇女及其婴儿是安全的. 该审查没有发现使用POC或早期启动会增加母乳养或婴儿不良结果的风险.
科学领域:
- 生殖健康 生殖健康
- 孕产妇和儿童的健康
- 药理学 药理学是指药理学的学科.
背景情况:
- 仅使用孕激素的避孕药 (POC) 是产后妇女的常见选择.
- 人们担心对母乳养和婴儿后果的潜在不良影响.
- 之前的审查已经评估了安全性,需要更新.
研究的目的:
- 系统地审查有关POC在母乳养期间使用安全性的证据.
- 评估POC使用与不使用相关的风险.
- 评估与POC早期 (6周前) 与晚期发病相关的风险.
主要方法:
- 进行全面的数据库搜索 (MEDLINE,EMBASE,Cochrane等) 在2023年9月之前.
- 包含了61篇文章,其中11篇是自上次审查以来的新文章.
- 对所有包含的研究进行数据提取和偏差风险评估.
主要成果:
- 没有发现对继续母乳养,补充或持续时间有重大不良影响.
- 没有发现对婴儿生长或疾病有重大不良影响.
- 对早产婴儿的证据也表明没有不良影响.
结论:
- 更新的系统审查证实了孕激素纯避孕药在哺乳妇女的安全性.
- 新发现的研究证实了以前发现没有不良影响的研究结果.
- 目前的证据包括早产婴儿的安全数据.
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