在皮下存储medroxyprogesterone乙酸后恢复生育能力:叙述性审查
Alfred Osoti1,2, Nancy Kidula3, Lauryn Busolo Mengesa4
1Obstetrics and Gynaecology, University of Nairobi, Nairobi, Kenya alfosoti@gmail.com.
BMJ sexual & reproductive health
|November 3, 2025
概括
discontinuing 皮下存储medroxyprogesterone acetate (DMPA SC) 药物后恢复生育能力与肌肉内配方类似. 对于DMPA SC,排卵的中位数时间为212天,与DMPA IM相比.
科学领域:
- 生殖健康 生殖健康
- 药理学 药理学是指药理学的学科.
- 避孕药是一种避孕药,用于避孕.
背景情况:
- 德波特 (DMPA) 是一种被广泛使用的注射避孕药.
- 皮下DMPA (DMPA SC) 为传统肌内 (IM) 配方提供了一种替代的注射途径.
- 了解DMPA停药后恢复生育能力对于计划生育至关重要.
研究的目的:
- 审查和综合现有证据,关于在停止使用DMPA SC 104 mg后恢复生育的时间.
- 为了比较DMPASC和DMPAIM配方之间恢复排卵的时间表.
主要方法:
- 在多个数据库 (PubMed,CINAHL,Web of Science等) 进行了全面的文献搜索. ) 的情况.
- 包括的研究使用了DMPASC的标准剂量,并报告了恢复排卵或生育能力.
- 分析了四篇相关文章的数据,将DMPA SC与DMPA IM进行了比较.
主要成果:
- 在停止DMPASC治疗后,排卵的中位数时间为212天.
- 这与DMPA IM (183天) 排卵的中位数时间没有统计学上显著的差异.
- 根据地区,BMI或年龄,没有观察到在排卵回归的显著差异.
结论:
- 皮下和肌肉内DMPA配方之间的选择似乎不会影响恢复生育的时间表.
- 排卵的中位数时间在DMPA SC和DMPA IM之间是可比的.
- 需要进一步研究怀孕的时间和剂量持续时间/频率的影响.
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