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Updated: Jan 12, 2026

An In Vitro Bladder Model of Catheter-Associated Urinary Tract Infection
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在尿路中利用微生物衍生的代谢物来防止感染诱导的导管化

L Beryl Guterman1, Madalyn Motsay1, Benjamin C Hunt1

  • 1Department of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA.

Nature communications
|November 3, 2025
PubMed
概括

研究人员确定了7种降低Proteus mirabilis尿酶活性的代谢物,这是导管相关尿路感染 (CAUTIs) 的关键因素. 这些化合物,特别是D-imidazole乳酸盐,在与现有治疗相结合时,有望预防导管堵塞和生物膜.

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