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Updated: Jan 12, 2026

Isolation, Culture, and Characterization of Prostate Cancer-Associated Fibroblasts
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在前列腺癌中,IGF-1调节癌细胞免疫逃避

Ashwin M Nandakumar1, Alessandro Barberis2, Jinseon Kim2

  • 1Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK. ashwin.nandakumar@nds.ox.ac.uk.

Scientific reports
|November 3, 2025
PubMed
概括

胰岛素样生长因子-1 (IGF-1) 通过抑制抗原呈现和上调PD-L1.1,损害前列腺癌 (PCa) 免疫反应. 这种机制有助于PCa.

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