幽灵半影模式在急性缺血性中风:特征和预后意义
Mercedes de Lera Alfonso1, Alicia Sierra-Gómez1, Ana I Calleja1
1Stroke Program, Department of Neurology, Hospital Clínico Universitario De Valladolid (HCUV), Instituto De Investigación Biomédica De Valladolid (IBIOVALL), Valladolid, Spain.
概括
幽灵半阴影模式 (GPP) 在接受内血管治疗的急性缺血性中风患者中发现了58%. 这种模式表明了对中风核心体积的低估,与更好的附带循环和安全的再输血有关.
科学领域:
- 神经辐射学神经辐射学
- 脑卒中成像 脑卒中成像
- 脑血管疾病 脑血管疾病
背景情况:
- 与非对比CT (NCCT) 相比,计算机断层扫描输液 (CTP) 上的幽灵半阴影模式 (GPP) 可以低估缺血核心体积.
- 了解GPP频率和影响因素对于急性缺血性中风 (AIS) 管理至关重要.
研究的目的:
- 在接受内血管治疗 (EVT) 的AIS患者中确定GPP的频率.
- 为了确定与GPP相关的基线因素.
- 评估GPP对EVT后临床和放射性结果的影响.
主要方法:
- 在173名AIS患者的NCCT,多相CT血管造影 (CTA) 和CTP分析,这些患者患有EVT治疗的大血管封闭.
- GPP定义为一个CT核心/CTP核心比>1.5.5.
- 评估附带状况,血栓迁移,对酶体血液瘤,低密度和功能结果 (修改90天的兰金度量表).
主要成果:
- 在100名 (58%) 患者中检测到GPP.
- 良好的抵押品流通 (OR 2.8) 和较低的NIHSS分数 (OR 0.9) 独立地与GPP相关.
- 预测GPP预测了更低的囊性血液瘤风险 (OR 0.43).
结论:
- 在接受EVT治疗的AIS患者中,GPP很常见,大约在一半的病例中发生.
- GPP与有利的抵押状况和血栓迁移有关.
- 在患有GPP的患者中,内血管再输是安全的.
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