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细胞微环境中的化学反应由结合聚合物指导向生物医学进步

Bowen Guo^1,2, Shuaian Shi^1,2, Hongrui Lin¹

¹Beijing National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P.R. China.

Angewandte Chemie (International ed. in English)

|November 4, 2025

概括

结合聚合物 (CPs) 为先进的生物医学应用提供了对细胞反应的精确控制. 这些材料正在彻底改变癌症和炎症的治疗方法,为个性化医疗铺平了道路.

科学领域:

生物材料科学生物材料科学
化学生物学化学生物学
纳米技术纳米技术

背景情况:

结合聚合物 (CPs) 具有用于细胞微环境调制的独特光电子特性.
化学反应器可以精确控制生物系统中的化学反应.

研究的目的:

审查近期联合聚合物导向生物医学策略的进展.
突出CP在光驱生物光催化,光动力学和光热疗法以及细胞调节中的作用.
讨论将CP集成到动态组件中,以进行最少的侵入性干预.

主要方法:

关于生物光催化和治疗中的CP应用的文献综述.
对生物过程的时空控制的CP机制的分析.
对CP平台的AI驱动分子设计的探索.

主要成果:

合成聚合物促进有针对性的氧化还原转换,气体生成和超分子相互作用.
将CP集成到组件中,可以对癌症,炎症和代谢障碍进行响应性干预.
人工智能和分子设计加速了基于CP的个性化医学的发展.

结论:

结合聚合物在治疗调制和诊断增强方面显示出转变潜力.
临床医生是开发下一代生物医学设备和个性化治疗的关键.
慢性病医生的跨学科创新正在推进微创生物医学策略.

关键词:

生物医学应用程序结合聚合物的聚合物.光电材料是一种光电材料.调节细胞微环境中的化学反应.

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