评估中欧和东欧老年人中可能不适当的药物使用情况
Jovana Brkic1,2, Jindra Reissigova1,3, Betul Okuyan4
1Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Kralove, Charles University, Hradec Kralove, Czechia.
Annals of medicine
|November 4, 2025
概括
潜在不合适的药物 (PIM) 使用在中欧和东欧的老年人中很常见,影响超过一半的患者. 诸如多药和并发症等因素增加了PIM风险,突出显示了需要更好的处方做法.
科学领域:
- 老年学和老年医学是老年学和老年医学.
- 临床药房 临床药房
- 公共卫生 公共卫生
背景情况:
- 潜在不适当的药物 (PIM) 使用是老年人的一个重大问题,导致不良的健康结果.
- 关于中东欧 (CEE) 国家的PIM患病率和相关因素的数据有限.
研究的目的:
- 确定在5个中东欧国家社区生活的老年人中使用PIM的流行率.
- 在这个人群中确定与PIM使用相关的风险和保护因素.
主要方法:
- 一项跨部门调查的二次分析 (Horizon 2020 EuroAgeism ESR7项目).
- 从保加利亚,克罗地亚,捷克,爱沙尼亚和塞尔维亚的2,155名老年人 (≥65岁) 收集的数据 (2019年2月至2020年3月).
- 使用欧盟(7)-PIM清单评估PIM患病率;用于风险因素分析的后勤回归.
主要成果:
- 整体PIM患病率为56.0%,国家之间存在显著差异 (捷克为29.5%,克罗地亚为70.0%).
- 通常使用的PIM包括二zepines,NSAIDs和长期PPI.
- 住所,并发症负担和多药物被确定为PIM使用的重要风险因素.
结论:
- 在中东欧国家的老年人中,使用PIM的流行率很高.
- 由于PIM流行率在不同国家之间存在很大差异,因此需要针对性的干预措施.
- 改善对老年人的药物处方对于提高医疗保健质量和患者结果至关重要.
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