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Updated: Jan 12, 2026

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
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结核菌菌FAS-II路径的目标是基于集成深度学习的潜在抗结核剂的识别

Animesh Chaurasia1,2, Mohd Mustkim Ansari3, Gunjan Tripathi3,2

  • 1Biochemistry and Structural Biology Division, CSIR-Central Drug Research Institute, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow, 226031, India.

Journal of computer-aided molecular design
|November 4, 2025
PubMed
概括

结核病药物发现面临抗药性挑战. 这项研究以机器学习和分子对接为目标,针对Mycobacterium结核病脂肪酸合成酶II (FAS-II) 途径,确定具有高达90%抑制活性的新型化合物.

关键词:
深度学习是一种深度学习.第二阶段的路径.结核病菌菌菌的结核病菌的结核病菌.虚拟选是一个虚拟的选.

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