两个阶段的集群采样评估SARS-CoV-2血清流行没有预先计数:马达加斯加的一个例子
Eva Lorenz1,2, John Amuasi3,4,5, Tiana Randrianarisoa6
1Infectious Disease Epidemiology, Bernhard Nocht Insitute for Tropical Medicine, Hamburg, Germany.
PloS one
|November 4, 2025
概括
一个新的现场测绘系统使得在马达加斯加实现了成本效益高,在人口普查前进行人口调查. 这种方法成功地映射了家庭并收集了SARS-CoV-2血清流行研究的数据,证明了可行性和代表性.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 地理信息系统 (GIS) 是指地理信息系统.
背景情况:
- 在资源有限的地区,以人口为基础的调查面临挑战,原因是无法获得详细的人口数据.
- 预计数通常是一个后勤障碍,增加成本和时间.
研究的目的:
- 开发和实施地理集群采样方法,用于没有预先计数的调查.
- 评估这种新的绘图和数据收集系统的可行性和潜在偏差.
- 使用这种方法在马达加斯加进行SARS-CoV-2血清流行调查.
主要方法:
- 在马达加斯加的城市Fianarantsoa进行的横截面观测研究 (2021年2月至6月).
- 随机生成的GPS坐标的群集 (fokontany) 的概率与大小比例采样.
- 带有OpenStreetMap的移动平板电脑用于实时导航,家庭识别和数据收集,功能离线.
- 综合现场映射系统用于在调查实施期间虚拟家庭映射.
主要成果:
- 在95.3%的GPS坐标上成功识别了家庭.
- 参与率很高:接触家庭的96.8% (674/696).
- 样本人口统计数据与人口普查数据相匹配,表明代表性;观察到参与率和财富之间的适度反相关性.
结论:
- 集成的现场映射系统为在资源有限的环境中,在没有预先编号的情况下进行两阶段集群采样提供了一个实用,具有成本效益的解决方案.
- 这种方法简化了物流,允许偏差评估,并创建了一个有价值的地理引用数据库.
- 该方法适用于COVID-19研究之外的各种公共卫生监测活动.
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