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Updated: Jan 12, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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IGF2BP3通过以m6A依赖的方式调节Semaphorin 4D稳定性来促进急性髓性白血病细胞的进展

Juan Li1, Shulan Shi2, Kefu Zhu3

  • 1Institute of Medicine, Dali University, Dali, Yunnan 671003, PR China; Institute of Pediatrics, The Kunming Children's Hospital, Children's Hospital affiliated to Kunming Medical University, Kunming, Yunnan 650228, PR China.

Leukemia research
|November 4, 2025
PubMed
概括

胰岛素生长因子2 mRNA结合蛋白3 (IGF2BP3) 通过稳定Sema4D mRNA.semaphorin 4D (Sema4D) 来促进儿科急性髓性白血病 (AML). 针对IGF2BP3/Sema4D轴可能提供新的AML治疗策略.

关键词:
急性髓性白血病 (AML) 是一种疾病.在 IGF2BP3BP3 中.在M6A甲基化中.塞马福林4D (Sema4D) 是一个

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