对患有大麻使用障碍的成年人进行简短的正念干预:随机临床试验
Valentina Lorenzetti1, Eugene McTavish2, Hannah Thomson2
1Neuroscience of Addiction and Mental Health Program, Healthy Brain and Mind Research Centre, Faculty of Health Sciences, Australian Catholic University, Melbourne, Australia; Clinical Psychopharmacology Unit, University College London, London, UK.
Drug and alcohol dependence
|November 4, 2025
概括
简短的基于正念的干预 (MBI) 并没有显著减少大麻使用频率,数量或大麻使用障碍 (CUD) 的成年人的渴望. 需要进一步的研究来探索CUD管理的有效干预措施.
科学领域:
- 成研究研究成研究
- 临床心理学 临床心理学
- 正念研究研究正念的研究.
背景情况:
- 大麻使用障碍 (CUD) 带来了渴望和减少使用的挑战,尽管有负面的结果.
- 需要对CUD进行可访问,可扩展和低成本的干预措施.
- 这项研究评估了针对CUD的简短的基于正念的干预 (MBI).
研究的目的:
- 为了确定一个简短的MBI是否会减少大麻的频率,数量和渴望.
- 将MBI与主动 (放松) 和被动 (控制) 条件进行比较.
主要方法:
- 这是一项双盲,随机对照试验,涉及66名患有CUD的成年人.
- 参与者被分配到MBI,放松或对照组.
- 主要结局是大麻使用日的变化;次要结局包括数量,渴望,正念和放松.
主要成果:
- 对于主要结果 (大麻使用频率) 没有发现显著的干预时间效应.
- 二次结果 (数量,渴望,放松,正念) 也没有显著的变化.
- 简要的MBI没有证明在减少大麻使用或相关症状方面有效.
结论:
- 简短的MBI在帮助CUD患者减少大麻消费方面并不有效.
- 研究结果表明,目前简短的MBI方法可能不足以治疗CUD.
- 对CUD的替代性或增强性干预措施进行进一步的研究是有必要的.
相关概念视频
Substance Use Disorders Affecting Sleep
394
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
394
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
658
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
Two synthetic agonists of THC,...
658


