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Updated: Jan 12, 2026

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一个骨髓状的Tet2-IL-1β轴通过限制色氨基酸细胞分化细胞分化的 катехоламин的刺激来调节肠道炎症

Deepika Sharma1, Ankit Malik1, Veronica Locher2

  • 1Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, USA; Department of Medicine, Committee on Immunology, Department of Pediatrics, Department of Pathology, University of Chicago, Chicago, IL, USA.

Immunity
|November 4, 2025
PubMed
概括

骨髓细胞特异性10-11转位甲基细胞二氧化酶2 (TET2) 的损失,保护其免受大肠炎的侵害. 这涉及降低肠染色胺细胞分化和胺释放,由髓质IL-1β向神经元发送信号介导.

关键词:
一个IL-1的IL-1.作为一个神经元,神经元是catecholaminergic的神经元.进入色素细胞的细胞.炎症性肠道疾病 炎症性肠道疾病肠道炎症是一种肠道炎症.巨细胞是什么?巨细胞是什么?

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