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Updated: Jan 12, 2026

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通过电子舌头对母中的苦味进行评估:循环德克斯复杂化的影响

Jihen Kallel¹, Salwa Ben Aissa², Basma Ousji²

¹Research Laboratory: Characterization, Applications, and Modeling of Materials, University of Tunis El Manar, Faculty of Sciences of Tunis, El Manar University Campus, Tunisia; Laboratory of Automation, Process Engineering, and Pharmaceutical Engineering (LAGEPP), University of Lyon 1, UMR 5007 CNRS, 43 Bd du 11 Novembre, 69622 Villeurbanne, France.

International journal of pharmaceutics

|November 4, 2025

概括

这项研究表明,环极素 (CD) 可以有效地掩盖草药的苦味. β-cyclodextrin (β-CD) 证明对马鲁染料最有效,验证了电子舌头对口味掩饰的评估.

科学领域:

制药科学制药科学
分析化学分析化学
食品科学食品科学食品科学

背景情况:

草本母具具有治疗效益,但患有明显的苦味,限制了患者的服从.
开发有效的苦味掩盖策略对于提高这些天然产品的味道至关重要.

研究的目的:

为了评估各种循环脱素 (CD) 在掩盖五种不同的草药母的苦味方面的有效性.
验证使用电子舌头系统与主要成分分析 (PCA) 结合使用,以评估复杂植物药物提取物的口味掩饰效果.

主要方法:

使用一个α-Astree II电子舌头,配有七个电位计传感器来分析苦味.
研究了β-cyclodextrin (β-CD),甲基化β-CD,xypropylβ-CD (HP-β-CD) 和xypropylγ-CD (HP-γ-CD) 的痛苦掩盖潜力.
在电子舌头数据和气色谱-质谱 (GC-MS) 上使用主要组件分析 (PCA) 进行复杂分析.

主要成果:

添加环氧德克斯显著降低了测试的草药染料的感知苦味.
苦味掩护的有效性因循环二烯的类型和特定的草药剂而异.
β-CD在降低马鲁母的苦味方面表现出最高的有效性,由GC-MS对马鲁复合的分析证实.

结论:

环极素是有效的药物,可以减轻草本母药的苦味.
通过PCA分析的电子舌头系统提供了一种可靠的方法,用于评估复杂的天然产品提取物中的口味掩饰策略.
这项研究验证了一种新的方法,用于提高具有治疗价值的草药配方的可口性.

关键词:

苦的味道和苦的味道.循环德克斯特林 (Cyclodextrins) 是一种循环德克斯特林.电子舌头 (E-tongue) 是一种语言.母乳染料是一种母乳染料.味道掩饰是一种口味掩饰.

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