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Updated: Jan 12, 2026

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癌症治疗中的DNA聚合酶甲基:作用机制和调节器开发

Junwei Wu1, Yi Xu2, Linlin Xiao1

  • 1Ganzhou Hospital-Nanfang Hospital, Southern Medical University, Ganzhou 341000, PR China.

Biochemical pharmacology
|November 4, 2025
PubMed
概括

DNA聚合酶甲基 (Polθ) 是一种合成致死性点,用于同源重组缺陷的癌症. 抑制Polθ利用其在DNA修复中的作用,为BRCA突变瘤提供了一个新的治疗策略.

关键词:
这是一种抗癌药物.对DNA损伤的反应反应基因聚合酶甲基的DNA聚合酶甲基.双链断裂是因为双链断裂.调制器调制器是一个模拟器.

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