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Updated: Jan 12, 2026

The c-FOS Protein Immunohistological Detection: A Useful Tool As a Marker of Central Pathways Involved in Specific Physiological Responses In Vivo and Ex Vivo
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The c-FOS Protein Immunohistological Detection: A Useful Tool As a Marker of Central Pathways Involved in Specific Physiological Responses In Vivo and Ex Vivo

Published on: April 25, 2016

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在先天性中央低通风综合征中缺失PHOX2B:这是足以引起病变的吗?

Kiyoshi Hayasaka1, Ayako Sasaki2, Yumiko Kishikawa2

  • 1Department of Pediatrics, Yamagata University School of Medicine, Yamagata, Japan. hayasaka@med.id.yamagata-u.ac.jp.

Journal of human genetics
|November 4, 2025
PubMed
概括

先天性中央低通风综合征 (CCHS) 主要是由PHOX2B突变引起的. 这项研究发现,PHOX2B删除虽然不能完全导致单独的CCHS,但可以损害呼吸控制的发展.

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Experimental Approach to Examine Leptin Signaling in the Carotid Bodies and its Effects on Control of Breathing05:45

Experimental Approach to Examine Leptin Signaling in the Carotid Bodies and its Effects on Control of Breathing

Published on: October 25, 2019

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Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures05:45

Delivery of In Vivo Acute Intermittent Hypoxia in Neonatal Rodents to Prime Subventricular Zone-derived Neural Progenitor Cell Cultures

Published on: November 2, 2015

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Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
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Cystic Fibrosis: Pathogenesis01:23

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
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There are various classifications for PH, each relating to different underlying causes and also...
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Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
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The pathophysiology of pneumonia involves the following steps:
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