在PET和SPECT成像中进行部分体积校正方法的批判性审查:好处,陷,挑战和未来前景
Mohammad Saber Azimi1, Arman Rahmim2, Hossein Arabi3
1Department of Medical Radiation Engineering, Shahid Beheshti University, Tehran, Iran.
European journal of nuclear medicine and molecular imaging
|November 4, 2025
概括
部分体积校正 (PVC) 方法提高了医学成像的定量准确性,但可以增加噪声. 最好的PVC方法取决于具体的临床应用,有些方法比常规实践更适合研究.
科学领域:
- 医学成像物理 医学成像物理
- 定量分析 定量分析
- 放射性药物科学 放射性药物科学
背景情况:
- 部分体积效应 (PVE) 是定量SPECT和PET成像中的一个重大挑战,影响准确性和可重复性.
- 现有的部分体积校正 (PVC) 方法在临床转化方面存在局限性.
研究的目的:
- 提供对PVC方法的临床导向评估.
- 评估PVC在神经学,心血管成像,瘤学和放射性药物治疗剂量计中的附加值.
- 确定各种PVC技术的临床准备和研究适用性.
主要方法:
- 将PVC方法分为基于重建的,基于后重建的和基于AI的/混合方法.
- 分类为解剖学和非解剖学方法.
- 基于定量准确性,病变检测能力,强度,概括性和临床准备性的系统比较.
主要成果:
- 在小型结构和溢出区域中,PVC方法提高了定量准确性,但可能会增加噪音和工件.
- 后重建方法对细分错误敏感;人工智能方法需要进一步验证和基准测试.
- 对人工智能驱动的PVC技术来说,通用性和解释性仍然是关键的挑战.
结论:
- 适合应用的PVC协议对于在各种临床领域进行可靠的定量成像至关重要.
- 并非所有PVC方法都是普遍有益的;有些可能会阻碍解释.
- 为研究和临床实践选择适当的PVC技术提供了指导,强调了未来发展的领域.
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