治疗前段新血管化多发性糖尿病视网膜病变的新血管性玻璃眼发病率和视觉结果
Emma Fiddimore1, Ahmed Al-Janabi1, Ramya Sulur Sundararajan1
1Cwm Taf Morgannwg University Health Board, Royal Glamorgan Hospital, Llantrisant, UK.
Eye (London, England)
|November 4, 2025
概括
在被治疗的多发性糖尿病视网膜病变中,前段新血管化如果局限于虹膜或角度,是可以管理的. 然而,外围前侧眼显著增加了新血管玻璃眼风险和视力损失.
科学领域:
- 眼科医生 眼科 眼科
- 糖尿病视网膜病变 - 糖尿病视网膜病变
- 前段新血管化 前段新血管化
背景情况:
- 前段新血管化 (ASNV),包括虹膜新血管化 (NVI) 和角度新血管化 (NVA),是多发性糖尿病视网膜病变 (PDR) 的并发症.
- 对PDR次要的ASNV的结果没有得到很好的描述.
- 这项研究评估了PDR二次性ASNV患者的视觉和眼内压力 (IOP) 结果.
研究的目的:
- 评估PDR继发ASNV的患者的视觉和IOP结局.
- 根据ASNV.的解剖阶段对结果进行分层.
- 评估新血管玻璃眼 (NVG) 的发生率.
主要方法:
- 来自72名接受治疗的PDR和ASNV患者的116只眼睛的回顾性队列研究.
- 眼睛分为三组:只有NVI;NVI和/或NVA没有外围前侧突 (PAS);和眼睛与PAS.
- 收集关于视力敏度 (VA),内视压力,治疗和疾病进展的数据. 随访时间中位数为42.5个月.
主要成果:
- 视觉结果和IOP控制在PAS患者的眼睛中明显恶化.
- 在PAS组中,最终的logMAR VA中位数为2.30,相比之下,只有0.36 (NVI) 和0.44 (NVI/NVA).
- 53%患有PAS的眼睛出现了NVG,而其他组的眼睛为0%. 在41%的PAS眼睛中,需要进行绿眼镜手术.
结论:
- 在接受治疗的PDR中,单独的NVI或NVA通常与视觉稳定性相容.
- 周围前 (PAS) 与高NVG发病率和视力低下有关.
- 早期镜检测和积极的治疗对于防止突角关闭至关重要.
相关概念视频
Open Angle Glaucoma: Treatment
951
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
951
Angle Closure Glaucoma: Treatment
1.1K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.1K
Glaucoma: Overview
1.2K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.2K


