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Updated: Jan 12, 2026

MicroRNA-based Regulation of Picornavirus Tropism
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Published on: February 6, 2017

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DICER1热点突变诱导3p微RNA通过Argonaute链交换机获得功能

Sharan Malagobadan1, Chunmei Shi1, Acong Yang1

  • 1RNA Mediated Gene Regulation Section, RNA Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.

Nature structural & molecular biology
|November 4, 2025
PubMed
概括

DICER1基因突变通过破坏微RNA (miRNA) 生物发生导致癌症. 这项研究表明,这些突变意外地激活了乘客3p-miRNAs,导致瘤发展.

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