沙特阿拉伯母乳养与自闭症谱状况之间的关联:一个病例控制研究
1Albidayah Breastfeeding and Women's Health Awareness Non-Profit Organization, Jeddah, Saudi Arabia. modiabatterjee@gmail.com.
International breastfeeding journal
|November 4, 2025
概括
减少母乳养的暴露可能会增加自闭症谱状况 (ASC) 的风险. 这项在沙特阿拉伯的病例控制研究发现,较短的母乳养时间和更高的ASC几率之间存在剂量反应关系.
科学领域:
- 神经发育障碍 神经发育障碍
- 儿童营养学 儿童营养学
- 公共卫生 公共卫生
背景情况:
- 自闭症谱状况 (ASC) 是一种影响社会沟通和行为的神经发育障碍.
- 关于早期营养,特别是母乳养和ASC风险的研究有限,特别是在非西方人群中.
研究的目的:
- 调查沙特阿拉伯母乳养做法与自闭症谱状况 (ASC) 之间的关联.
- 探索母乳养期间减少暴露和ASC风险之间的剂量反应关系.
主要方法:
- 在沙特阿拉伯进行了一项无与伦比的病例控制研究.
- 数据是通过在线问卷从有和没有ASC的孩子的母亲收集的.
- 哺乳期的暴露被分类 (排他性,占主导地位,部分,没有) 并使用逻辑回归分析.
主要成果:
- 观察到一种剂量反应关系:降低母乳养暴露与更高的ASC几率相关 (趋势的OR为1.58).
- 与纯母乳养相比,部分母乳养 (OR: 2.49) 和没有母乳养 (OR: 3.46) 与ASC概率的增加显著相关.
- 在多变量调整后,关联仍然显著 (部分:OR 2.28;没有:OR 2.86).
结论:
- 减少母乳养暴露与自闭症谱状况 (ASC) 的几率增加有关.
- 研究结果表明,母乳养对ASC有潜在的保护作用.
- 由于研究的局限性,如潜在的反向因果关系,应谨慎解释结果.
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