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Updated: Jan 12, 2026

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis
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人类临床前多发性骨髓瘤体外模型用于疾病建模和治疗查

Mikayla Ybarra1,2, Jaehun Lee1, Yun-Ya Chen1

  • 1Department of Cancer Sciences, Cleveland Clinic Research, Cleveland, OH, 44195, USA.

Journal of biological engineering
|November 4, 2025
PubMed
概括

先进的人性化模型对于理解多发性骨髓瘤 (MM) 进展和耐药性至关重要. 目前的系统无法复制骨髓微环境,阻碍了这种血液恶性瘤的治疗发展.

关键词:
三维细胞培养的3D细胞培养疾病建模 疾病建模多发性骨髓瘤是一种多发性骨髓瘤.器官在芯片上的器官治疗测试治疗测试.

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