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Updated: Jan 12, 2026

The Use of Primary Human Fibroblasts for Monitoring Mitochondrial Phenotypes in the Field of Parkinson's Disease
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转酶1通过代谢重编程和自-溶解体通路影响帕金森病的发病

Zixin Tan1, Huimin Hu1, Hao Chen1

  • 1Department of Neurology, The First Affiliated Hospital of Guangzhou Medical University, No. 151 Yanjiang Road, Guangzhou, 510120, China.

Acta neuropathologica communications
|November 4, 2025
PubMed
概括

向Transaldolase1 (TAL1) 显示出对帕金森病 (PD) 治疗的前景. 抑制TAL1可以增强自 - lysosomal功能和能量代谢,减少神经退行和α-synuclein聚合在PD模型.

关键词:
自 - 溶酶体通路自 - 溶酶体通路代谢重编程是一种代谢重编程.帕金森病是帕金森氏症的一种疾病.转胺酶1 转胺酶1

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