功能与左心室低电压区域负荷之间的关联在阳性心房动中
Shaochong Deng1, Xiang Tan1, Yuxuan Wang1
1Division of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
概括
低功能,以估计的膜过率 (eGFR) 表示,与较大的左心房低压区域 (LVA) 相关,在患有动心房 (PAF) 的老年患者中. 这一发现可能有助于在切除手术前预测LVA负担.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學.
- 电力生理学 电力生理学
背景情况:
- 周围肺静脉隔离 (CPVI) 与左心房低压区域 (LVA) 修改治疗心房动 (PAF).
- 预测LVA负担前消去是非常具有挑战性的.
- 慢性病 (CKD) 与左心房LVA患病率的增加有关.
研究的目的:
- 调查PAF老年患者功能和LVA负担之间的关系.
- 为了确定功能是否可以预测LVA负担在这个患者群体.
主要方法:
- 对435名PAF患者的老年患者进行了回顾性分析,他们接受了切除.
- 根据LVA负担 (≤5%,5%-10%,10%-15%,>15%) 将患者分为四组.
- 分析了估计的膜过率 (eGFR) 和LVA负担之间的相关性.
主要成果:
- 随着LVA负担的增加,人们观察到eGFR的逐渐下降.
- 在最低和最高的LVA负担组之间显著的eGFR差异 (p=0.003).
- eGFR预测LVA负担>10%,最佳切断值为75.7mL/min/1.73m2,显示54.2%的灵敏度和80.4%的特异性.
结论:
- 降低eGFR与老年PAF患者的LVA负担较高有关.
- 功能,特别是eGFR,可以作为显著LVA负担的预测因素.
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