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Updated: Jan 12, 2026

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
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Published on: December 23, 2016

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硫尼尔化衍生物向谷氨降解酶:在癌症中进行氧化调节的潜在策略

Erbay Kalay1, Halide Sedef Karaman2, Osman Nuri Aslan3

  • 1Department of Material and Material Processing Technologies, Kars Vocational School, Kafkas University, Kars, Turkey.

Chemical biology & drug design
|November 5, 2025
PubMed
概括

新的硫尼尔化类型被合成并测试为谷氨缩酶 (GR) 抑制剂,一种在瘤中过度表达的酶. 化合物6a显示强大的GR抑制和抗癌活性,表明作为候选药物的潜力.

关键词:
细胞活力的细胞活力.酶抑制抑制酶的抑制.谷氨减少酶可以减少谷氨.分子对接的分子对接.硫尼尔化的使用方法

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