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Updated: Jan 12, 2026

An HS-MRM Assay for the Quantification of Host-cell Proteins in Protein Biopharmaceuticals by Liquid Chromatography Ion Mobility QTOF Mass Spectrometry
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An HS-MRM Assay for the Quantification of Host-cell Proteins in Protein Biopharmaceuticals by Liquid Chromatography Ion Mobility QTOF Mass Spectrometry

Published on: April 17, 2018

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基于模型的深度Q网络以指导儿童克朗氏病的因弗力西马布剂量

Kei Irie1, Phillip Minar2,3, Jack Reifenberg4

  • 1Division of Translational and Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Clinical pharmacology and therapeutics
|November 5, 2025
PubMed
概括

这项研究引入了深度Q网络 (DQN),用于克罗恩病的个性化因弗利克西马布剂量,自动化模型知情精度剂量 (MIPD). 人工智能模型成功优化了药物疗法,改善了目标实现和现实世界的低谷水平.

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