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化疗对转移性结直肠癌的乘客突变的影响

Marium T Siddiqui1, Matthew A Cottam1, Muhammad Bilal Mirza1

  • 1Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.

Molecular oncology
|November 5, 2025
PubMed
概括

化疗可以减少转移性结直肠癌 (mCRC) 的乘客突变,特别是在微卫星稳定 (MSS) 病例中. 这一发现表明,乘客突变和瘤突变负担 (TMB) 可以指导MSS mCRC.的未来治疗策略.

关键词:
化疗 化疗是一种化学疗法.结肠直肠癌是什么意思转移 转移 转移 转移乘客的突变 乘客的突变整体外基因组测序的测序

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