内脏和皮下脂肪积累的性别特异性差异及其与代谢异常的关联
Isa Galvão Rodrigues1,2, Gabriela Maria Pereira Floro Arcoverde1,3, Camila Lima Chagas do Nascimento3
1Department of Nutrition, Emergency Cardiology Unit of the University of Pernambuco, Recife, State of Pernambuco, Brazil.
Journal of obesity
|November 5, 2025
概括
男性的内脏腹部脂肪组织 (VAT) 比女性更高,但女性的心脏代谢风险更差. 这项研究强调了脂肪分布的性别差异及其对健康的影响.
科学领域:
- 内分泌学 在内分泌学.
- 心脏病学 心脏病学
- 代谢健康 代谢健康
背景情况:
- 身体脂肪的分布在性别之间有所不同,但机制和心脏代谢后果需要进一步研究.
- 内脏腹部脂肪组织 (VAT) 和皮下脂肪组织 (SAT) 在代谢健康中起着不同的作用.
研究的目的:
- 调查增值税和SAT度的性别差异.
- 确定男性和女性的VAT,SAT和心脏代谢风险因素之间的关联.
主要方法:
- 一个大学医院253名门诊患者 (≥20年) 的横截面研究.
- 使用超声波测量高可靠性 (> 0.90) 的VAT和SAT.
- 评估了人口,人类,行为和生化变量.
主要成果:
- 男性的平均增值税 (7.3厘米与6.0厘米) 更高,而女性的平均SAT (3.4厘米与2.7厘米) 更高.
- 在女性中,增值税与不良的代谢标志物 (甘油三,葡萄糖,HbA1c) 相对相关,与HDL相反.
- 增值税/SAT比率预测女性的胆固醇,甘油三,葡萄糖和HbA1c水平较高;男性没有显示与增值税相关的显著代谢变化.
结论:
- 尽管BMI相似,但男性的增值税较高,而女性的新陈代谢表现较差,尽管增值税较低.
- 脂肪分布的性别特异性显著影响心脏代谢风险.
- 考虑到性别特异性的脂肪分布的有针对性的干预措施可能会改善代谢健康结果.
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