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Updated: Jan 12, 2026

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通过转录组学预测代谢偏好:一种数据驱动的方法,以将代谢特征与基因表达特征对齐

Lente J S Lerink1,2, Marleen J de Winter1, Jaap A Bakker3

  • 1Department of Surgery & Transplant Centre, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands.

Biochemistry and biophysics reports
|November 5, 2025
PubMed
概括

哺乳动物在器官中的代谢特征并不直接与基因表达保持一致. 了解这些复杂的代谢模式对于改善ex vivo模型系统及其可翻译性至关重要.

关键词:
动脉静脉测量 动脉静脉测量代谢流量是指代谢的流量.代谢过程中的代谢.基质偏好 基质偏好转录组的个人资料.文字转录学 (Transcriptomics) 是一个学科.

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Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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