在阻塞性与选择性结肠直肠癌中的临床结果和术后发病率:十年后期分析
Sreejith Kannummal Veetil1, Deepak Jain1, Parvez David Haque1
1General Surgery, Christian Medical College and Hospital, Ludhiana, IND.
Cureus
|November 5, 2025
概括
紧急结直肠癌 (CRC) 呈现与阻塞导致更糟糕的结果. 与选择性手术病例相比,阻塞患者面临更高的死亡率,更多的感染,更长的住院时间,以及较低的治疗完成率.
科学领域:
- 结肠直肠癌 (CRC) 的研究.
- 手术瘤学手术瘤学
- 临床结果研究研究的临床结果.
背景情况:
- 呈现时阻塞性结肠直肠癌 (CRC) 与晚期疾病和增加风险有关.
- 将紧急阻塞与选择性切除结果进行比较对于患者管理至关重要.
研究的目的:
- 为了比较患有紧急大肠阻塞的结直肠癌 (CRC) 患者的术前和临床结果,与接受计划性选择性切除的患者进行比较.
主要方法:
- 对237个成年CRC切除的回顾性队列研究.
- 70个突发性阻塞病例与167个选择性病例的比较.
- 对人口统计,症状,瘤阶段,手术细节,死亡率,SSI,住院和辅助治疗完成情况的分析.
主要成果:
- 阻塞患者更常见的是晚期瘤阶段 (第四阶段:40.0%vs.28.7%),并出现腹痛和吐等症状.
- 紧急病例的30天死亡率显著增加 (25.7%与3.6%相比),手术部位感染增加 (28.6%与15.0%相比),住院时间延长 (15.6与10.3天相比).
- 在受阻组中,辅助疗法完成率较低 (52.9%vs75.4%).
结论:
- 阻塞性结肠直肠癌 (CRC) 呈现显著恶化术后死亡率,发病率和治疗完成.
- 早期检测和优化术后护理对于改善阻塞性CRC的结果至关重要.
- 对于患有阻塞性结直肠癌的患者来说,高体积中心的治疗可能是有益的.
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