[一个博士学位完成. 慢性扩散性硬化下骨髓炎的治疗策略]
M M van de Meent1, J P R van Merkesteyn1, N M Appelman-Dijkstra2
1the Department of Oral Diseases, Jaw and Facial Surgery, Leiden University Medical Center (LUMC).
Nederlands tijdschrift voor tandheelkunde
|November 5, 2025
概括
慢性扩散性硬化下骨髓炎,也称为慢性肌炎,在保守和双酸盐治疗中显示出有前途的结果. 只有由于下变形导致的面部不对称性,才建议进行手术.
科学领域:
- 口腔和牙面部外科手术
- 牙科研究 牙科研究
- 病理学 病理学 病理学
背景情况:
- 长期扩散性硬化下骨髓炎 (CDSO) 是一种罕见的疾病,原因不明.
- 肌过度活跃是导致CDSO的潜在因素,也称为慢性肌炎.
- 目前的文献介绍了CDSO的各种治疗方式.
研究的目的:
- 系统地审查有关慢性扩散性硬化骨髓炎治疗选择的文献.
- 评估CDSO保守,双酸盐和外科手术治疗的疗效.
- 为管理CDSO提供基于证据的建议.
主要方法:
- 对慢性扩散性硬化骨髓炎研究的系统文献综述下.
- 对保守疗法治疗结果的分析 (闭合,物理治疗,咨询).
- 对CDSO进行双酸盐治疗和外科手术的评估.
主要成果:
- 保守治疗导致67%的CDSO患者的症状减少.
- 所有患者在接受双酸盐治疗后都经历了症状改善.
- 手术治疗对CDSO的成功率很低,重塑手术仅适用于面部不对称.
结论:
- 对于CDSO来说,保守的管理应该是6-12个月的初始方法.
- 双酸盐治疗对于改善CDSO症状是有效的.
- 对CDSO的手术只适用于导致面部不对称的下变形病例.
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