优化心力衰竭管理:洞察GDMT和循环利尿剂在专业心力衰竭诊所的使用
Evelyne Meekers1,2, Zara Arcidiacono2, Romy Baptist2
1Department of Cardiology, Ziekenhuis Oost-Limburg A.V., Genk, Belgium.
Acta cardiologica
|November 5, 2025
概括
心力衰竭诊所正在优化护理,减少循环利尿剂的使用,增加指南导向医学治疗 (GDMT). 这一转变旨在改善患者的治疗结果,并减少对利尿剂的依赖.
科学领域:
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
- 临床医学 临床医学
背景情况:
- 循环利尿剂通常用于心力衰竭 (HF),但与较差的结果有关.
- 循环利尿剂的处方率很高,尽管有证据,但仍然存在.
- 指南导向医学疗法 (GDMT) 可以减轻循环利尿剂的需要.
研究的目的:
- 在比利时HF诊所评估循环利尿剂和GDMT处方模式.
- 将这些模式与最近HF试验的发现进行比较.
主要方法:
- 1000名连续HF患者 (LVEF ≤50%) 从门诊HF诊所的未来注册.
- 通过电子健康记录收集的数据,包括人口统计,药物和心声回声.
主要成果:
- 54.3%的患者患有HF,射出率降低;年龄中位数为72,LVEF中位数为45%.
- 处方GDMT的比例很高 (68.7%的三倍/四倍治疗).
- 与最近的试验相比,循环利尿剂的使用量显著下降 (27%).
结论:
- 高频率诊所在优化患者护理方面取得了进展.
- 在HF诊所中以患者为中心的方法可以减少循环利尿剂的依赖.
- 进一步优化护理和并发症管理是必不可少的.
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