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Timothy Shim¹, Kevin Wong¹, Michael J Ruckenstein¹

¹Department of Otorhinolaryngology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

The Laryngoscope

|November 5, 2025

概括

化 (NaF) 可能有助于稳定耳硬化患者的感觉神经听力损失 (SNHL). 这篇论文回顾了当前的文献,以建立在耳硬化管理中NaF使用的最佳实践.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
药理学药理学是一个学科.
听力学听力学是指听力学.

背景情况:

耳硬化是导电性听力损失的常见原因,但也可能影响神经传感听力.
化 (NaF) 已被研究其在耳硬化中稳定神经感应听力损失 (SNHL) 的潜力.
目前的临床指导方针和关于NaF用于耳硬化症的共识缺乏.

研究的目的:

解释有关化 (NaF) 治疗耳硬化的现有文献.
确定基于证据的最佳实践,用于NaF在治疗耳硬化中的利用.
为了解决缺少在耳硬化治疗中使用NaF的既定指南的问题.

主要方法:

对调查NaF和耳硬化症的研究进行系统文献综述.
分析临床试验数据和关于NaF有效性和安全性的病例报告.
综合发现,以确定最佳的治疗方案.

主要成果:

有证据表明,NaF可能会稳定或减缓SNHL在某些耳硬化患者的进展.
在不同研究中,NaF治疗的最佳剂量和持续时间仍然是可变的.
潜在的副作用和长期安全性需要进一步调查.

结论:

纳氧化作为稳定SNHL在耳硬化中的辅助疗法具有前景.
需要对在耳硬化症中使用NaF的标准化指南.
需要进一步的研究来证实疗效,最佳剂量和安全性.

关键词:

听力损失听力损失是什么耳硬化症是什么耳硬化症这种疾病叫做otospongiosis.化的化是一种化.这是一种阶段性切除术.这是一次脚切除术 (Stepedotomy).

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