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Updated: Jan 12, 2026

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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Published on: September 8, 2012

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一种具有环核酶活性的病毒 SAVED 蛋白降解了 CRISPR 第二信使 cA4

Marta Orzechowski1, Ville Hoikkala1, Haotian Chi1

  • 1School of Biology, University of St Andrews, North Haugh, St Andrews, KY16 9ST, U.K.

The Biochemical journal
|November 5, 2025
PubMed
概括

病毒使用一种新型的抗CRISPR蛋白,AcrIII-2,来降解循环四甲酸 (cA4) 信号. 这种病毒蛋白通过向cA4第二信使来抑制III型CRISPR-Cas免疫系统.

关键词:
克里斯普尔是什么意思?克里斯普尔是什么意思?保存的域名 保存域名环核酶是指环核酶的组成部分.第三种类型的CRISPR防御.

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