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准怀孕期间对不确定性的不容忍:一项随机对照试验,以预防产后焦虑症

Melissa Furtado^1,2,3, Benicio N Frey^1,4,5, Briar E Inness^1,2

¹Women's Health Concerns Clinic, St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada.

The Journal of clinical psychiatry

|November 5, 2025

概括

针对怀孕期间不容忍不确定性的认知行为疗法可以预防产后焦虑症. 与通常的护理相比,这种干预显著降低了孕妇的焦虑风险和症状.

科学领域:

围产期心理健康问题
焦虑症焦虑症焦虑症
预防性心理健康策略预防性心理健康策略

背景情况:

产后焦虑很普遍,并且与父母和婴儿的不良结果有关.
对产后焦虑的预防策略研究不足.
不确定性不耐受 (IU) 是产后焦虑的潜在风险因素.

研究的目的:

调查怀孕期间针对不容忍不确定性 (CBT-IU) 的6周认知行为治疗方案是否可以降低产后焦虑症的风险.
评估CBT-IU对焦虑,抑郁和情绪调节的影响.

主要方法:

一个概念验证随机对照试验 (RCT) 涉及37名怀孕个体 (14-32周怀孕) 具有较高的IU.
参与者被随机分配到6次单独的CBT-IU或通常照顾 (CAU) 的6次会议中.
主要结局是产后焦虑症的发生率;次要结局包括IU,焦虑,抑郁和情绪调节的变化.

主要成果:

接受CBT-IU的参与者中没有一个患有分娩后焦虑症,而CAU组的这一比例为31.6% (P<.001).
CBT-IU显著降低了IU (P=.003),担心症状 (P<.001),情绪失调 (P=.018),以及面试官评估的焦虑症状 (P<.001).
接受CBT-IU的参与者报告了高度的治疗满意度.

结论:

用CBT-IU针对怀孕期间的不确定性不容忍似乎是预防产后焦虑症的有效策略.
这项概念验证研究支持需要大规模的RCT来确认CBT-IU的疗效.
CBT-IU显示出作为围产期心理健康的预防性干预措施的前景.

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