由于增加了动脉硬性,COVID-19导致血压控制更加困难
Marialuisa S Marozzi1,2, Ilaria Fucile3, Immacolata Panettieri4
1Unit of Internal Medicine "Guido Baccelli", Department of Precision and Regenerative Medicine and Ionian Area - (DiMePRe-J), University of Bari Aldo Moro, AUOC Policlinico Di Bari, University Hospital Policlinico Di Bari, Piazza Giulio Cesare, 11, 70124, Bari, Italy.
Internal and emergency medicine
|November 5, 2025
概括
在高血压患者中,COVID-19感染与血压升高和血管硬有关. 这项研究发现,SARS-CoV-2幸存者需要更多的药物来控制他们的高血压.
科学领域:
- 心血管医学 心血管医学
- 传染性疾病 传染性疾病
- 高血压研究 高血压研究
背景情况:
- COVID-19 感染可以影响血管系统,可能会影响血压控制.
- SARS-CoV-2 对动脉高血压的长期影响仍在调查中.
研究的目的:
- 为了研究COVID-19感染和高血压患者的血压控制之间的相关性.
- 评估SARS-CoV-2对血管功能和药物要求的影响.
主要方法:
- 一项多中心研究招募了185名先前感染SARS-CoV-2的高血压患者 (第一组) 和97名负控人 (第二组).
- 在两个时间点 (T0和T1) 评估血压,高血压心肌病 (HTN-CM) 诊断,吸烟状态和抗高血压药物使用情况.
- 测量脉冲波速度 (PWV),以评估血管硬度.
主要成果:
- 第1组 (COVID-19阳性) 与第2组相比,表现出缩血压升高和HTN-CM发病率较高.
- COVID-19幸存者需要更多的抗高血压药物,特别是血管激素受体阻断剂,并表现出增加的PWV,表明血管硬性更大.
- 在第一组感染后观察到吸烟者的减少和HTN-CM诊断的增加.
结论:
- 在高血压患者中,COVID-19感染与血管硬度增加和血压升高有关.
- 由于持续的血管变化,SARS-CoV-2幸存者可能需要加强抗高血压治疗.
- 需要进一步的研究来了解COVID-19的长期血管后果.
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