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Updated: Jan 12, 2026

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
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强力感应GPCR LPHN2对于正常的听觉功能是不可或缺的

Shu-Hua Zhou1, Ming-Wei Wang2, Zhi-Chen Song3

  • 1NHC Key Laboratory of Otorhinolaryngology, Qilu Hospital of Shandong University, and New Cornerstone Science Laboratory, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China; Department of Physiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan 250012, China; State Key Laboratory of Vascular Homeostasis and Remodeling, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, Beijing 100191, China.

Cell reports
|November 5, 2025
PubMed
概括

研究人员发现,G蛋白结合受体LPHN2对于听力至关重要. LPHN2与TMC1通道进行物理相互作用,使机电转导成为可能,并防止小鼠的听力损失.

关键词:
在CP:神经科学.耳毛细胞是耳的毛细胞.在GPCR中,GPCR是指GPCR.在 LPHN2 的情况下,LPHN2在MET中,MET是MET.听到 听到 听到 听到 听到 听到 听到机械敏感的机械敏感的

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