关于亚洲炎症性肠病先进治疗现状的问卷调查
Yosuke Toya1, Akiko Shiotani2, Shoko Ono3
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Yahaba, Japan.
Digestion
|November 5, 2025
概括
亚洲的医生主要使用抗TNFα疗法治疗炎症性肠病 (IBD). 对于性结肠炎 (UC) 和克罗恩病的治疗选择.
科学领域:
- 胃肠病学和肝病学 胃肠学和肝病学
- 临床治疗学 临床治疗学
- 免疫学 免疫学 免疫学
背景情况:
- 全球炎症性肠病 (IBD) 发病率上升,包括性结肠炎 (UC) 和克罗恩病 (CD).
- 在选择最佳的先进疗法方面存在挑战,因为有很多选择和各种各样的医疗保健系统.
研究的目的:
- 评估亚洲九个国家的IBD先进疗法的现状.
- 了解医生对治疗剂选择,生物标志物和监测方式的看法.
主要方法:
- 在九个亚洲国家对医生进行了问卷调查.
- 收集的数据主要集中在先进IBD治疗的当前状态和选择标准上.
主要成果:
- 反TNFα抗体是UC和CD最常选择的先进疗法.
- 老年UC患者接受了特定疗法 (抗α4β7-整体素,抗IL-12/23p40),考虑到安全性.
- 简氏激酶抑制剂被用作严重病例的二线治疗;CRP和内镜是常见的监测工具.
结论:
- 该调查提供了关于亚洲当前IBD治疗先进实践的见解.
- 建议为IBD治疗选择开发特定于区域的,基于证据的算法.
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