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2005年至2017年间内细胞质精子注射的使用趋势和指示:全州范围的描述性队列分析.
Aleah Kink1, Parinaz Mehdipour1, Richard J Hiscock2
1Melbourne Medical School, The University of Melbourne, Parkville, Victoria, Australia.
The Australian & New Zealand journal of obstetrics & gynaecology
|November 5, 2025
概括
在澳大利亚,细胞内质精子注射 (ICSI) 的使用显著增加,大多数周期缺乏明确的医疗必要性. 这一趋势突出显示了随着时间的推移,非必要的ICSI程序的增加.
科学领域:
- 生殖医学 生殖医学
- 不孕症治疗 不孕症治疗
- 辅助生殖技术 辅助生殖技术
背景情况:
- 内细胞质精子注射 (ICSI) 最初是针对男性因子不孕症而开发的.
- 全球ICSI的采用量有所增加,扩展到非必要的受精病例.
研究的目的:
- 分析ICSI利用的时间趋势.
- 检查澳大利亚ICSI的指示变化.
主要方法:
- 在澳大利亚维多利亚州进行试管婴儿的妇女的描述性队列研究 (2005-2017年).
- 分析ICSI吸收趋势和报告的使用指示.
- 纳入标准:导致怀孕20周后分娩的周期.
主要成果:
- ICSI使用率从2005年的60.6%增加到2017年的79.5%.
- 诸如捐赠精子,PGT,女性因素和晚年孕产妇年龄等迹象增加.
- 2008年以后",未指明"的适用性变得占主导地位.
- 男性因子不孕症指标下降,而丸精子检索保持稳定.
结论:
- 在研究期间,ICSI的总体使用量增加了18.9%.
- 很大一部分ICSI循环在医学上是不适用的.
- 该研究突出显示,越来越多的ICSI应用往往是不必要的.
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