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Updated: Aug 9, 2026

Determination of Molecular Structures of HIV Envelope Glycoproteins using Cryo-Electron Tomography and Automated Sub-tomogram Averaging
07:29

Determination of Molecular Structures of HIV Envelope Glycoproteins using Cryo-Electron Tomography and Automated Sub-tomogram Averaging

Published on: December 1, 2011

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艾滋病毒包膜与细胞GRP78相互作用的计算特征作为潜在的进入机制

Wael M Elshemey1, Hamdy I A Mostafa2, Abdo A Elfiky2

  • 1Department of Physics, Faculty of Sciences, Islamic University in Madinah, Madinah 42351, Saudia Arabia.

Cell stress & chaperones
|November 5, 2025
PubMed
概括

人类免疫缺陷病毒 (HIV) 使用其包膜蛋白与宿主细胞上的葡萄糖调节蛋白78 (GRP78) 结合. 艾滋病毒包膜蛋白的R4区域被确定为GRP78.8的关键结合部位.

关键词:
GRP78,病毒的识别.艾滋病病毒 艾滋病病毒 艾滋病病毒分子对接是分子对接.分子动力学模拟模型结构生物信息学 结构生物信息学

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Leaky Scanning02:28

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...