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Updated: Jan 12, 2026

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小P110通过向线粒体功能障碍来缓解SPG15患者的iPSC衍生的神经元的轴突退化

Bavavarshini Tamilselvam1, Gitika Thakur1, Ruth Mathew1

  • 1Department of Biomedical Sciences, University of Illinois College of Medicine Rockford, Rockford, IL 61107, USA.

Neurobiology of disease
|November 5, 2025
PubMed
概括

线粒体功能障碍在SPG15遗传性性中驱动神经退行. 用P110向线粒体形态的向显示了保护神经元和减轻疾病进展的希望.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.轴突退化 轴突退化遗传性性护理症是遗传性的线粒体功能障碍 线粒体功能障碍在SPG15中,SPG15是SPG15中的一个.这些是iPSCs.

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