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Updated: Jan 12, 2026

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HIF1α/PRDX1轴通过DRP1脱SUMOylation和线粒体分裂驱动肺血管重塑

Yingjuan Wu1, Yi Liu2, Lina Shan3

  • 1Department of Emergency, Panzhihua Central Hospital, Panzhihua, 61700, China.

Biochimica et biophysica acta. Molecular basis of disease
|November 5, 2025
PubMed
概括

肺高血压 (PH) 涉及血管重塑. 研究人员发现,过氧化-1 (PRDX1) 通过调节线粒体动力学来驱动这个过程,为PH提供了潜在的治疗标.

关键词:
DRP1 DRP1 的使用方法这就是HIF1α.在PRDX1中,肺高血压是一种肺高血压.这就是SUMOylation的作用.

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