关于肺癌查的结构化叙事审查:当前的证据,临床实践的影响和多学科工作组和患者代表的实施见解
Georgia Hardavella1, Kyriaki Tavernaraki2, Dimitrios Lioumpas3
16th Department of Respiratory Medicine, "Sotiria" Athens' Chest Diseases Hospital, Athens, Greece.
概括
肺癌查 (LCS) 的好处超过了风险. 将戒烟融入LCS计划至关重要,尽管最佳查标准和持续时间需要进一步研究.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 肺癌查 (LCS) 的实施在全球范围内有所不同,国家计划有限,数据稀缺.
- 生命科学领域正在不断发展,需要更新的证据综合.
研究的目的:
- 为专家和患者确定的12个优先LCS主题提供最新的文献概述.
- 综合临床实践和关于LCS实施的健康决策的证据.
- 在证据有限或混合的情况下讨论局限性并得出最佳实践的结论.
主要方法:
- 一个多学科工作组 (TF) 专家组和患者代表确定了12个关键兴趣领域.
- 进行了系统的文献搜索,随后对现有证据进行了选,审查和综合.
主要成果:
- 国家LCS计划很少;然而,LCS的好处和风险已经确立.
- 建议使用低剂量计算机断层扫描 (LDCT) 与戒烟,以获得最佳的LCS结果.
- 包括标准,查频率,风险模型和生物标志物需要进一步验证和标准化.
结论:
- LCS的好处超过了潜在的风险.
- 对于特定的纳入标准,计划持续时间和生物标志物在LCS中的应用的证据是有限的.
- 将戒烟融入LCS计划是必不可少的,目前正在进行的研究预计将澄清剩余的不确定性.
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