运动穿皮氧气压测量与恒定和分级跑步机测试之间的关系
Cindy Vannier1,2, Adélaïde Guézais2, Marjolaine Talbot2
1Vascular Surgery Unit, University Hospital, Rennes, France.
Vascular medicine (London, England)
|November 5, 2025
概括
使用分级跑步机协议进行运动穿皮氧气压测量 (Exercise-TcPO2) 与诊断外周动脉疾病 (PAD) 的常量负荷测试有很高的相关性. 为加德纳-斯金纳协议提出了一个新的值.
科学领域:
- 血管医学 血管医学
- 诊断成像 诊断成像 诊断成像
- 运动生理学 运动生理学
背景情况:
- 运动穿皮氧气压测量 (Exercise-TcPO2) 是用于诊断下肢外周动脉疾病 (PAD) 的验证工具.
- 以前的验证使用了常量负载跑步机协议,但其与分级协议的实用性仍然未知.
- 这项研究研究了使用分级加德纳-斯金纳协议与常量修改的Strandness协议相比,使用运动-TcPO2的研究.
研究的目的:
- 为了在怀疑PAD的患者中比较分级 (Gardner-Skinner) 和常负荷 (修改的Strandness) 跑步机测试之间的运动-TcPO2结果.
- 为了确定两个协议的休息氧气压力 (DROP) 指数下降之间的关系和一致性.
- 通过加德纳-斯金纳协议提出PAD的诊断值.
主要方法:
- 40名疑似PAD患者在同一天接受了修改后的Strandness和Gardner-Skinner跑步机测试.
- 静止氧气压下降指数 (DROP) 在两次测试中都在部和小腿水平上测量.
- 在延伸性测试中,DROP指数≤-15 mmHg被认为是PAD诊断的阳性.
主要成果:
- 来自加德纳-斯金纳 (DROPGard) 测试的DROP值和修改的延展性 (DROPStrand) 测试 (DROPGard = 0.647 × DROPStrand - 1.858) 之间发现了强烈的相关性.
- 在DROPGard和DROPStrand之间的平均差异为-4.3 ± 7.3 mmHg.
- 积极和消极的协议率分别为78.0%和86.3%,kappa系数为0.65.
结论:
- 使用加德纳-斯金纳分级协议获得的运动-TcPO2结果与修改的Strandness常量负载协议高度相关.
- 建议DROPGard值≤-12 mmHg作为使用Gardner-Skinner测试的PAD潜在诊断值.
- 建议进一步验证这个拟议的值与成像黄金标准.
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