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Updated: May 11, 2026

Genetic Manipulation in Δku80 Strains for Functional Genomic Analysis of Toxoplasma gondii
09:52

Genetic Manipulation in Δku80 Strains for Functional Genomic Analysis of Toxoplasma gondii

Published on: July 12, 2013

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对TgGSK3的结构和功能表征,TgGSK3是一种Toxoplasma gondii中的可药物酶

Silvia Diaz-Martin1, Christopher Swale1, Valeria Bellini1

  • 1Institute for Advanced Biosciences (IAB), Team Host-pathogen interactions and immunity to infection, INSERM U1209, CNRS UMR5309, University Grenoble Alpes, Grenoble, France.

Nature communications
|November 5, 2025
PubMed
概括

一个药物重定向屏幕确定了LY2090314作为毒素菌和Cryptosporidium的强有力的抑制剂. 这项研究揭示了TgGSK3激酶是主要的分子标,为这些杂寄生虫提供了有前途的治疗途径.

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QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii11:37

QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii

Published on: June 22, 2017

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Determination of Chemical Inhibitor Efficiency against Intracellular Toxoplasma Gondii Growth Using a Luciferase-Based Growth Assay09:49

Determination of Chemical Inhibitor Efficiency against Intracellular Toxoplasma Gondii Growth Using a Luciferase-Based Growth Assay

Published on: April 29, 2020

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