经验采样为基础的饮食评估方法 (ESDAM) 对双重标记的水,尿蛋白和生物标志物进行验证的议定书
Joke Verbeke1, Kristin Verbeke2, Bart Van der Schueren1,3
1Department of Chronic Diseases and Metabolism, Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Nutrition journal
|November 5, 2025
概括
基于实验采样的饮食评估方法 (ESDAM) 是一款用于跟踪饮食的新应用程序. 这项研究验证了ESDAM与生物标志物和其他方法对比,以确保准确的饮食摄入量评估.
科学领域:
- 营养科学 营养科学
- 生物标志物研究 生物标志物研究
- 数字健康数字健康
背景情况:
- 开发准确,低成本的饮食评估工具至关重要.
- 基于实验采样的饮食评估方法 (ESDAM) 是一种新的应用程序,旨在近乎实时评估饮食摄入量.
- 本研究重点是使用客观生物标志物验证ESDAM的准确性.
研究的目的:
- 根据已建立的饮食评估方法和客观生物标志物,验证基于实验采样的饮食评估方法 (ESDAM).
- 评估ESDAM在测量能量和蛋白质摄入量的准确性.
- 评估ESDAM捕获的营养素和食品组消费模式.
主要方法:
- 该研究方案涉及对ESDAM与三个24小时饮食召回 (24-HDR),双重标记的水,尿,血清胡卜素和红细胞膜脂肪酸进行验证.
- 主要结局包括能量和蛋白质摄入量,与分别标记双重的水和尿相比.
- 二次结果评估营养素和食物组摄入量,以胡卜素和脂肪酸作为生物标志物. 持续的葡萄糖监测将评估合规性.
主要成果:
- 该协议概述了ESDAM的广泛验证.
- 该研究采用了最先进的验证技术,包括生物标志物,如双重标记的水,尿,胡卜素和脂肪酸.
- 验证的目的是量化ESDAM和24-HDR相对于真正的饮食摄入量的测量误差.
结论:
- 本协议详细介绍了针对自我报告和客观措施的新型ESDAM的全面验证.
- 这项研究的优势在于使用先进的生物标志物来评估饮食摄入量.
- 一个限制是ESDAM可重复性评估的排除.
相关概念视频
Effects of EDTA on End-Point Detection Methods
Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a result, EDTA...
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a result, EDTA...
Serum Laboratory Studies, Stool Test, Breath Test
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...


