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来自乌克兰Dnipro的CF儿科患者的呼吸道病原体的基因组和表型表征

Dmytro Stepanskyi1, Oksana Ishchenko2, Patrick McGann3

  • 1Department of Microbiology, Virology, Immunology, Epidemiology and Biomedical Physics and Informatics, Dnipro State Medical University, Dnipro, Ukraine. dstepanskiy@gmail.com.

BMC pulmonary medicine
|November 5, 2025
PubMed
概括

囊性纤维化患者的慢性感染是复杂的. 这项研究确定了特定的细菌菌株,包括金黄色葡萄球菌ST398的小殖民地变体 (SCV) 和高毒的Klebsiella pneumoniae,突出了基因组监测的必要性.

关键词:
囊性纤维化症是什么基因组特征的表征伪omonas aeruginosa 这种类型的病毒.小殖民地变种黄金葡萄球菌黄金葡萄球菌.乌克兰 乌克兰 乌克兰 乌克兰

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Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
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