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三糖糖-腰围动态和心血管风险:全国纵向研究

Jiana Zhong¹, Dixing Liu², Xinyi Huang³

¹Department of Endocrinology, Binhaiwan Central Hospital of Dongguan, Dongguan, China.

Lipids in health and disease

|November 5, 2025

概括

三糖糖-腰围 (TyG-WC) 指数的变化与糖尿病前期和糖尿病患者的心血管疾病 (CVD) 风险有关. TyG-WC指数可能有助于这些高风险群体的早期心血管疾病检测.

科学领域:

内分泌学在内分泌学.
心脏病学心脏病学
公共卫生公共卫生

背景情况:

心血管疾病 (CVD) 与甘油三糖 (TyG) 指数有关.
有限的研究存在于甘油三糖-腰围 (TyG-WC) 指数和心血管疾病,特别是在糖尿病和糖尿病前期.
这项研究调查了Tyg-WC指数变化与葡萄糖失调患者心血管疾病之间的关联.

研究的目的:

分析TyG-WC指数变化与心血管疾病发病率之间的关联.
为了评估TyG-WC指数作为潜在的早期检测标志物对CVD在个人的葡萄糖失调.

主要方法:

来自中国健康与退休长度研究 (CHARLS) 的2428名糖尿病前期和糖尿病患者的纵向分析.
K-意味着集群以确定TyG-WC指数轨迹;累计的TyG-WC指数分为三位数.
比例危险模型和ROC曲线分析,以评估心血管疾病风险和辨别能力.

主要成果:

与较低稳定的轨迹相比,较高的TyG-WC轨迹 (中等稳定和高稳定) 与心血管疾病风险增加有显著的关联.
高稳定的TyG-WC组显示出最高的心血管疾病发病率 (P趋势<0.001).
累积的TyG-WC第三种T2和T3显示CVD,中风和心脏事件风险明显高于T1;累积的TyG-WC比基线WC,TyG-WC和TyG.有更好的心血管疾病辨别能力.

结论:

泰格-WC指数的变化与糖尿病前期和糖尿病患者的心血管疾病风险密切相关.
泰格-WC指数显示,它有可能成为这些人群中早期发现心血管疾病风险的新指标.

关键词:

查尔斯查尔斯查尔斯查尔斯查尔斯查尔斯心血管疾病是什么心血管疾病糖尿病糖尿病糖尿病 K-表示集群.长期变化长期变化糖尿病前期的情况.三甘油糖 - 腰围周长

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