通过辅助生殖技术怀孕的双胞胎怀孕的产妇和产周结局与自发受孕:基于人口的队列研究
Eunhee Yu1, Hyun Joo Lee1, Sul Lee1
1Department of Obstetrics and Gynecology, Pusan National University Hospital Biomedical Research Institute, Pusan National University School of Medicine, Busan, Korea.
Obstetrics & gynecology science
|November 6, 2025
概括
与自发妊娠相比,辅助生殖技术 (ART) 双胞胎怀孕面临更高的并发症风险,如孕前和紧急剖腹产. 这凸显了需要专门的产前护理,特别是对于年长的母亲.
科学领域:
- 生殖医学 生殖医学
- 产科和妇科 产科和妇科
- 围产期健康 围产期健康
背景情况:
- 辅助生殖技术 (ART) 越来越多地用于怀孕.
- 双胞胎怀孕带有固有的风险.
- 比较ART怀孕与自发怀孕双胞胎的结果对于优化护理至关重要.
研究的目的:
- 为了比较ART怀孕和自发怀孕双胞胎怀孕之间的产科和周产期结果.
- 为了确定与双胞胎怀孕中ART怀孕相关的特定风险.
- 为了告知临床指南和患者咨询.
主要方法:
- 使用全国范围的韩国国家医疗保险服务数据 (2017-2021) 进行回顾性队列研究.
- 确定的双胞胎怀孕和分类的受孕类型 (ART与自发).
- 使用多变量逻辑回归分析了包括流产,孕前,GDM,紧急CS,IUGR和宏观的结果.
主要成果:
- 在ART怀孕的双胞胎中,胎盘前,孕前,孕期糖尿病 (GDM),紧急剖腹产 (CS) 和子宫内生长限制 (IUGR) 的风险明显更高.
- 在35岁及以上的女性中,在ART组中,孕前和紧急CS的风险更为明显.
- 针对每个并发症,报告了特定的调整几率比率 (aOR) 和置信区间 (CI).
结论:
- 双胞胎怀孕与产妇和产周并发症的增加有关.
- 这些发现强调了对ART双胞胎进行量身定制的产前护理和监测的需要.
- 晚年母亲的年龄进一步增加了风险,需要谨慎管理.
更多相关视频
相关概念视频
Regression Toward the Mean
6.8K
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when...
6.8K
In Vitro Fertilization
868
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
868
Teratogenicity
3.9K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
3.9K
Behavioral Genetics and Its Designs
981
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
981


